Our Discovery Process
A More Efficient and Effective Drug Discovery Process
CHEMSAS® can change the way the pharmaceutical industry identifies high potential compounds.
CHEMSAS is a robust proprietary computational process for accelerated drug discovery and optimization. Using a unique combination of traditional and modern pharmacology principles, statistical modeling, medicinal chemistry and machine learning technologies, COTI is able to discover, profile, and optimize novel compounds in an accelerated manner.
CHEMSAS allows COTI to advance only those molecules with a high probability of successful development for a specific target therapy into the drug development pipeline. This is facilitated by evaluating molecules for efficacy, toxicity, oral availability and metabolism prior to synthesis and in vivo testing.
CHEMSAS can also be utilized to:
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find novel uses for known compounds to extend the patent life of a current drug franchise
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profile and optimize compounds currently in clinical studies to identify and to help solve pharmacokinetic problems
To request more information about licensing an optimized library of lead molecules or to discuss utilizing CHEMSAS for screening and optimization purposes, please contact Michael Barr, Director of Business Development and Marketing.